Best Bets for NCAA Basketball Picks Against the Spread for Friday, November 22

Published 6:22 pm Thursday, November 21, 2024

ATS Pick: Pittsburgh -5.5 vs. LSU

• Matchup: Pittsburgh Panthers vs. LSU Tigers
• Time: 2:30 PM ET
• Date: November 22
• Computer Projection: Pittsburgh by 18.8 points (Bet now on BetMGM)
• Spread: Pittsburgh (-5.5)
• TV Channel: CBS Sports Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Southern Illinois +17.5 vs. Florida

• Matchup: Southern Illinois Salukis at Florida Gators
• Time: 7:00 PM ET
• Date: November 22
• Computer Projection: Florida by 5.1 points (Bet now on BetMGM)
• Spread: Florida (-17.5)
• TV Channel: SEC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Elon +14.5 vs. Notre Dame

• Matchup: Elon Phoenix at Notre Dame Fighting Irish
• Time: 7:30 PM ET
• Date: November 22
• Computer Projection: Notre Dame by 2.5 points (Bet now on BetMGM)
• Spread: Notre Dame (-14.5)
• TV Channel: ACC Network Extra

ATS Pick: CSU Bakersfield +4.5 vs. FGCU

• Matchup: CSU Bakersfield Roadrunners at Florida Gulf Coast Eagles
• Time: 11:00 AM ET
• Date: November 22
• Computer Projection: CSU Bakersfield by 6.5 points (Bet now on BetMGM)
• Spread: FGCU (-4.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

ATS Pick: Duke +1.5 vs. Arizona

• Matchup: Duke Blue Devils at Arizona Wildcats
• Time: 10:30 PM ET
• Date: November 22
• Computer Projection: Duke by 8.9 points (Bet now on BetMGM)
• Spread: Arizona (-1.5)
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

ATS Pick: William & Mary +15.5 vs. NC State

• Matchup: William & Mary Tribe at NC State Wolfpack
• Time: 7:00 PM ET
• Date: November 22
• Computer Projection: NC State by 5.6 points (Bet now on BetMGM)
• Spread: NC State (-15.5)
• TV Channel: ACC Network Extra

ATS Pick: Longwood +6.5 vs. UAB

• Matchup: Longwood Lancers vs. UAB Blazers
• Time: 12:30 PM ET
• Date: November 22
• Computer Projection: Longwood by 3 points (Bet now on BetMGM)
• Spread: UAB (-6.5)
• TV Channel: ESPN Networks

ATS Pick: UCF +3.5 vs. Wisconsin

• Matchup: Wisconsin Badgers vs. UCF Knights
• Time: 5:00 PM ET
• Date: November 22
• Computer Projection: UCF by 5.3 points (Bet now on BetMGM)
• Spread: Wisconsin (-3.5)
• TV Channel: CBS Sports Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Nebraska +10.5 vs. Creighton

• Matchup: Nebraska Cornhuskers at Creighton Bluejays
• Time: 8:00 PM ET
• Date: November 22
• Computer Projection: Creighton by 4.2 points (Bet now on BetMGM)
• Spread: Creighton (-10.5)
• TV Channel: Fox Sports 1
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Campbell +25.5 vs. Ohio State

• Matchup: Campbell Fighting Camels at Ohio State Buckeyes
• Time: 6:00 PM ET
• Date: November 22
• Computer Projection: Ohio State by 20.4 points (Bet now on BetMGM)
• Spread: Ohio State (-25.5)
• TV Channel: BTN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)